American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Nov 2007
Comparative StudyComparison of cost, effectiveness, and safety of injectable anticoagulants used for thromboprophylaxis after orthopedic surgery.
The cost, effectiveness, and safety of injectable anticoagulants used for thromboprophylaxis after orthopedic surgery were compared. ⋯ A retrospective analysis of inpatient billing data showed that, among orthopedic surgery patients, fondaparinux was associated with lower institutional cost and a lower frequency of VTE than were dalteparin, enoxaparin, and unfractionated heparin. Dalteparin was associated with a lower rate of major bleeding events than was fondaparinux, but there were no significant differences in such events among fondaparinux, enoxaparin, and unfractionated heparin.
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Am J Health Syst Pharm · Nov 2007
ReviewAntiemetic care for patients with breast cancer: focus on drug interactions and safety concerns.
The drug interactions and adverse events that should be considered when individualizing antiemetic therapy for patients undergoing treatment for breast cancer are reviewed. ⋯ Antiemetic treatment is essential for patients with breast cancer who are undergoing moderately to highly emetogenic cytotoxic treatment. When selecting an antiemetic, clinicians must select an agent that provides optimal protection against nausea and vomiting while avoiding drug-drug interactions and additional adverse events.
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Am J Health Syst Pharm · Nov 2007
Comparative StudyInstruction on compounded sterile preparations at U.S. schools of pharmacy.
The extent of didactic and laboratory instruction related to compounded sterile preparations (CSPs) provided by U.S. schools of pharmacy was studied. ⋯ A survey sent to deans of pharmacy schools revealed that instruction provided to pharmacy students in preparing CSPs varied widely. Only about a sixth of respondents believed that their students were adequately trained in compounding sterile preparations before graduation.
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Am J Health Syst Pharm · Nov 2007
ReviewBotulinum toxin type A for treatment of refractory gastroparesis.
The clinical efficacy and adverse reactions of botulinum toxin type A for refractory gastroparesis are discussed. ⋯ Botulinum toxin type A may be effective in the management of refractory gastroparesis; however, large, double-blind, placebo-controlled trials are needed to confirm this.