Current opinion in pulmonary medicine
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Chemotherapy has produced only modest survival benefits in patients with advanced non-small cell lung cancer. Several new chemotherapeutic agents developed in the past few years have shown promising activity in non-small cell lung cancer. ⋯ Chemotherapy has made a much stronger impact in small cell lung cancer, but the majority of patients still die from disease. The new chemotherapeutic agents may also contribute to improved survival of patients with small cell lung cancer, especially when used in combination with thoracic radiotherapy in those who present with limited disease.
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The diagnosis, staging, and follow-up of lung cancer is a clinical and therapeutic challenge. Recent radiographic advances are critical to the management of patients with lung cancer. This review focuses on state-of-the-art chest imaging modalities, including plain radiography, computed tomography; magnetic resonance imaging, as well as the newest technique, positron-emission tomography, and discusses the current literature.
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The use of lasers in the diagnosis and treatment of lung neoplasms has just surpassed a 20-year experience. This paper reviews recent developments in the use of lasers in the palliative treatment of advanced tracheobronchial tumors and pleural mesothelioma. The role of bronchoscopic laser therapy relative to other endobronchial treatment modalities such as stent placement and brachytherapy is presented. Finally, the potential use of lasers in photodetection and curative treatment of early lung cancer is discussed.