Current opinion in critical care
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Refractory cardiac arrest still has a grave prognosis under conventional cardiopulmonary resuscitation (CPR). We present the recent studies in extracorporeal CPR (ECPR) for the treatment of refractory cardiac arrest. ⋯ In this review, survival after ECPR was generally best after pediatric IHCA (38-57%), followed by adult IHCA (34-46%) and then adult OHCA (4-36%). Most studies reported that longer conventional CPR duration was associated with mortality after ECPR; however, there was no consensus on the optimal conventional CPR duration before ECPR initiation. Future studies might focus on the indications for ECPR, which should maximize the survival potential after ECPR while reducing the overuse of this resource-intensive facility.