Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
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Exp. Clin. Endocrinol. Diabetes · Feb 2020
The Variation of Disulfides in the Progression of Type 2 Diabetes Mellitus.
The purpose of this study was to examine thiol-disulfide balance in patients with type 2 diabetes mellitus. ⋯ A disequilibrium between thiol-disulfide pairs occurs in patients with type 2 diabetes mellitus, and a gradual increase to disulfide levels may contribute to the disease's severity. Deteriorated thiol-disulfide homeostasis may be relevant to the pathophysiology of type 2 diabetes mellitus.