Journal of pediatric hematology/oncology
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J. Pediatr. Hematol. Oncol. · Dec 2008
Case ReportsAn uncommon presenting sign of Langerhans cell histiocytosis: focal perianal lesions without systemic involvement.
A 3-year-old boy presented with constipation and perianal lesions resembling condyloma latum. The results of a biopsy of the perianal lesions confirmed the diagnosis of Langerhans cell histiocytosis (LCH). ⋯ In patients with functional constipation associated with perianal lesions that do not respond to conventional treatment, LCH should be part of the differential diagnosis. A simple biopsy of the external lesion and histologic examination of the mass are essential for diagnosis.