Journal of pediatric hematology/oncology
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J. Pediatr. Hematol. Oncol. · Oct 2013
The use of complementary and alternative medicine by irish pediatric cancer patients.
The use of complementary and alternative medicine (CAM) in the Irish pediatric cancer setting has not previously been established. ⋯ The high prevalence of CAM use demonstrated in this study and particularly the high use of CAM medication therapies underlines the importance of physicians asking routinely about CAM use in this population.
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J. Pediatr. Hematol. Oncol. · Oct 2013
The effects of propofol and ketamine on the cytokine levels of children with acute lymphoblastic leukemia.
The immune system of children with acute lymphoblastic leukemia (ALL) is affected by both the underlying disease and the chemotherapy. Children with ALL receive sedation for diagnostic and therapeutic procedures, which may contribute to immune competence alteration. The effects of propofol-ketamine combination on the immune system of children with ALL have not been investigated. ⋯ Sedation with propofol-ketamine combination did not modify the plasma concentration of the most measured cytokines and the T helper 1/2 ratio in children with ALL. There was a significant reduction in IL-8 concentration 24 hours after BMA associated with the concomitant administration of steroids and methotrexate. These data suggest that sedation with propofol-ketamine combination may not affect the immediate outcome of children with ALL.