Inflammation research : official journal of the European Histamine Research Society ... [et al.]
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To assess the involvement of spinal inducible nitric oxide synthase (iNOS) in inflammation and nociception. ⋯ The results show that iNOS is upregulated in the inflamed tissue and spinal cord with a similar time course. The effects obtained with L-NIL suggest that iNOS differently contributes to the inflammatory and nociceptive response induced by zymosan.