Inflammation research : official journal of the European Histamine Research Society ... [et al.]
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To investigate the effects of recombinant human growth hormone (rhGH) on rat acute lung injury (ALI). ⋯ Treatment with rhGH can significantly attenuate lung injury in the endotoxemic rats, which may be attributed to the reduction of the expression of ICAM-1, the influence on the adhesion and activation of PMNs, the inhibition of the activation of NF-kappaB and the regulation of the transcription of certain proinflammatory cytokines.