Inflammatory bowel diseases
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Inflamm. Bowel Dis. · Jul 2012
Identifying youth nonadherence in clinical settings: data-based recommendations for children and adolescents with inflammatory bowel disease.
To examine the validity of patient self-report of thiopurine adherence in pediatric inflammatory bowel disease (IBD) against an objective electronic monitoring adherence measure, and to investigate the role of youth and maternal involvement in remembering to take daily medications as predictors of medication adherence. ⋯ The current findings provide evidence that clinicians who work with children and adolescents with IBD may benefit from modifying their approach to nonadherence screening. Asking about youth involvement in remembering daily medications may be more informative than asking them to recall their medication-taking behavior over the last week in identifying those at highest risk for nonadherence.
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Inflamm. Bowel Dis. · Jul 2012
Infliximab does not affect postoperative complication rates in Crohn's patients undergoing abdominal surgery.
In patients with Crohn's disease (CD), the effect of anti-tumor necrosis factor alpha (TNF-α) antibody therapy on postoperative complications remains unclear. We aimed to determine the effects of infliximab on postoperative complication rates in patients undergoing abdominal surgery for CD. ⋯ Infliximab does not affect postoperative complication rates, suggesting no need to alter surgical management in these patients.