Inflammatory bowel diseases
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Inflamm. Bowel Dis. · Oct 2019
Multicenter Study Comparative Study Observational StudyComparative Efficacy of Vedolizumab and Adalimumab in Ulcerative Colitis Patients Previously Treated With Infliximab.
Adalimumab (ADA) and vedolizumab (VDZ) have shown efficacy in moderate to severe ulcerative colitis (UC) patients who failed infliximab (IFX). Although, a comparative efficacy evaluation of ADA and VDZ in this clinical setting is currently missing. ⋯ Vedolizumab might be the therapy of choice in those UC patients who showed secondary failure to IFX.