Inflammatory bowel diseases
-
Inflamm. Bowel Dis. · Apr 2019
Validation and Investigation of the Operating Characteristics of the Ulcerative Colitis Endoscopic Index of Severity.
The Ulcerative Colitis Endoscopic Index of Severity (UCEIS) is a novel instrument to evaluate endoscopic disease activity. It has been demonstrated to outperform the more widely used Mayo endoscopic score (MES) in predicting long-term prognosis, including the need for colectomy. Despite its potential benefits, many clinicians still prefer to use MES because its operating characteristics are better defined and its grades are more readily applicable to clinical decision-making. The aims of our study were to quantify the UCEIS cutoff most closely associated with the need for treatment escalation and to perform a validation exercise using MES and clinical, biochemical, and histological measures of disease activity. ⋯ 10.1093/ibd/izy325_Video_1 izy325.video1 5849933952001.