Neurobiology of learning and memory
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Neurobiol Learn Mem · Jul 1998
Review Comparative StudyA comparative perspective on motor learning.
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Neurobiol Learn Mem · Jan 1998
Comparative StudyFurther support for nitric oxide-dependent memory processing in the day-old chick.
There is considerable evidence that nitric oxide activity is essential for memory formation, particularly from studies using inhibitors of nitric oxide synthase. The particular stage of memory formation requiring nitric oxide activity has not, however, been systematically investigated. ⋯ This effect was replicated with a second inhibitor, l-NG-nitroarginine (1 mM), and counteracted by the NO donor, sodium nitroprusside (150 microM). These findings provide covergent evidence that nitric oxide activity plays a critical role in the consolidation of memory in the day-old chick.
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Neurobiol Learn Mem · Nov 1997
A brain of her own: a neural correlate of song assessment in a female songbird.
The song control region in the avian forebrain is a series of discrete, interconnected nuclei mediating song learning and production. It has been studied in males or in species where both sexes sing. Little is known about the neural correlates of song perception in nonsinging females, often the intended recipients of song. ⋯ We found that volume of lMAN was monomorphic in cowbirds. Moreover, the volume and neuronal number of female lMAN were positively correlated with selectivity of copulatory responding. The results provide strong evidence of nonsinging female's use of "song" control nuclei for song perception without the possibility of song production.
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Neurobiol Learn Mem · Jan 1995
ReviewProperties and mechanisms of long-term synaptic plasticity in the mammalian brain: relationships to learning and memory.
Long-term potentiation (LTP) in the hippocampus and long-term depression (LTD) in the cerebellum are two forms of long-lasting synaptic plasticity that currently serve as our primary experimental models of learning and memory formation in mammals. In recent years, there have been considerable advances in our understanding of the cellular and molecular mechanisms of these and other forms of synaptic plasticity. This article presents an overview of these developments, considers the relationship of long-term synaptic plasticity mechanisms to learning and memory in view of these developments, and suggests future directions for research in this rapidly growing area of neuroscience.