Investigative radiology
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Investigative radiology · Oct 2002
Pharmacokinetic modeling of Gd-DTPA extravasation in brain tumors.
The endothelial permeability of brain tumors affecting the blood-brain barrier can be quantified using dynamic contrast enhanced MR imaging. ⋯ The fast component is probably caused by extravasation into viable tissue (enhanced in meningiomas) while the slow one probably reflects increased diffusion distances into poorly perfused tissue such as necrotic areas in glioblastomas.