Investigative radiology
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Investigative radiology · Aug 2011
Immediate intramyocardial bone marrow-derived mononuclear cells implantation in minipig myocardium after permanent coronary artery ligation: magnetic resonance imaging with histopathologic and immunochemical correlation.
: To investigate the effects of immediate intramyocardial implantation of autologous bone marrow-derived mononuclear cells (BMDMNCs) in minipig myocardium after coronary artery ligation with magnetic resonance imaging (MRI), histopathologic, and immunochemical studies. ⋯ : After myocardial infarction in a swine model, immediate intramyocardial BMDMNCs implantation may promote neovascularization with resultant improvement in LV function, perfusion, and myocardial viability as demonstrated on cardiovascular MRI.