Investigative radiology
-
Investigative radiology · Nov 2012
Peripheral zone prostate cancer localization by multiparametric magnetic resonance at 3 T: unbiased cancer identification by matching to histopathology.
The aim of this study was to assess the diagnostic accuracy of peripheral zone prostate cancer localization by multiparametric magnetic resonance (MR) at 3 T using segmental matching of histopathology and MR images to avoid bias by image features in selection of cancer and noncancer regions. ⋯ By selecting histopathology defined cancer and noncancer areas without influence of image contrast, this study objectively reveals that all investigated MR parameters have the ability to separate cancer from noncancer areas in the peripheral zone individually and that any combination is better than T2WI alone.