Investigative radiology
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Investigative radiology · Mar 2014
Multicenter StudyValue of 3-T multiparametric magnetic resonance imaging and magnetic resonance-guided biopsy for early risk restratification in active surveillance of low-risk prostate cancer: a prospective multicenter cohort study.
The objective of this study was to evaluate the role of 3-T multiparametric magnetic resonance imaging (MP-MRI) and magnetic resonance-guided biopsy (MRGB) in early risk restratification of patients on active surveillance at 3 and 12 months of follow-up. ⋯ Application of MP-MRI and MRGB in active surveillance may contribute in early identification of patients with GGP 4 or 5 containing cancers at 3 months of follow-up. If, during further follow-up, a PI-RADS score of 1 or 2 continues to have a negative predictive value for GGP 4 or 5 containing cancers, a PI-RADS standardized reported MP-MRI may be a promising tool for the selection of prostate cancer patients suitable for active surveillance.
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Investigative radiology · Mar 2014
Feasibility of single-source dual-energy computed tomography for urinary stone characterization and value of iterative reconstructions.
The purposes of this study were to demonstrate the feasibility and accuracy of single-source dual-energy (DE) computed tomography (CT) with sequential data acquisition and a coregistration motion correction algorithm for urinary stone characterization and to evaluate the value of iterative reconstructions (IRs) in DE imaging. ⋯ Our study indicates that single-source dual-energy CT with sequential acquisitions at different energy levels and a coregistration motion correction algorithm is feasible and accurate for characterizing urinary stone composition on the basis of phantom evaluation. As compared with reconstructions with FBP, the use of IR in dual-energy CT reduces noise, improves overall image quality and visibility of stones particularly in large phantoms, and helps to avoid false classifications of urinary stones.