Investigative radiology
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Investigative radiology · Nov 2008
Clinical TrialMultidetector computed tomography in reperfused acute myocardial infarction. Assessment of infarct size and no-reflow in comparison with cardiac magnetic resonance imaging.
(1) To determine the accuracy of delayed enhancement multidetector computed tomography (MDCT) in measuring the extent of acute myocardial infarct and no-reflow areas using cardiac magnetic resonance imaging (MRI) as standard of reference and (2) to define the optimum timing between injection and MDCT image acquisition to characterize infarcted myocardium and no-reflow areas after reperfusion therapy. ⋯ In ST segment elevation myocardial infarction patients contrast-enhanced MDCT is an accurate method for characterizing and sizing myocardial infarct and no-reflow. Contrast-enhanced MDCT performed 5 minutes after injection yields a higher signal-to-noise ratio and image quality than the 10 minutes time point with no difference in the extent of infarct measurement.
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Investigative radiology · Oct 2008
Comparative StudyComputed tomography, positron emission tomography, positron emission tomography/computed tomography, and magnetic resonance imaging for staging of limited pleural mesothelioma: initial results.
To evaluate and compare the role of computed tomography (CT), positron emission tomography (PET), PET/CT, and magnetic resonance imaging (MRI) in the correct staging of patients with limited malignant pleural mesothelioma (MPM). ⋯ PET/CT makes it possible to stage patients with limited MPM with high accuracy and low interobserver variability.
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Investigative radiology · Oct 2008
Evaluation of ovarian tumors by proton magnetic resonance spectroscopy at three Tesla.
The purpose of this study was to determine the feasibility of acquiring in vivo proton magnetic resonance spectroscopy of ovarian lesions at a magnetic field strength of 3 Tesla (T). The goal was to provide potentially diagnostic biochemical information that may aid in the characterization of ovarian neoplasms detected during clinical magnetic resonance imaging scanning. ⋯ Spectroscopy of ovarian masses can be recorded at 3.0 T with acceptable spectral quality and good signal-to-noise ratio. There are stringent technical considerations to be considered in obtaining good spectral quality. Further experience with a larger and more biologically variable range of tumors needs to be undertaken to determine the final clinical utility of this technique, but initial results from this small cohort are promising.
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Investigative radiology · Oct 2008
Randomized Controlled Trial Comparative Study Clinical TrialIntra-individual crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine for contrast-enhanced magnetic resonance angiography of the supraaortic vessels at 3 Tesla.
To compare gadobenate dimeglumine (Gd-BOPTA) and gadopentetate dimeglumine (Gd-DTPA) for contrast-enhanced magnetic resonance (MR) angiography of the supraaortic vessels at 3 Tesla. ⋯ Significantly improved image quality and contrast enhancement is achieved at 3T with 0.1 mmol/kg Gd-BOPTA compared with 0.1 mmol/kg Gd-DTPA.
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Investigative radiology · Sep 2008
Comparative StudyDiffusion tensor magnetic resonance imaging of the human calf: comparison between 1.5 T and 3.0 T-preliminary results.
To compare diffusion tensor-magnetic resonance imaging (DT-MRI) of human calf muscles at 1.5 T and 3.0 T, and to measure a number of quantitative parameters to characterize diffusion anisotropy in organized muscle tissue using similar imaging parameters. ⋯ This study demonstrates useful parameters to perform DT-MRI at 1.5 T and 3.0 T. DT-MRI at 1.5 T and 3.0 T provide in vivo validation of quantitative structural analysis of human skeleletal muscle.