Investigative radiology
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Investigative radiology · Jun 2008
Quantification of lung volume at different tidal volumes and positive end-expiratory pressures in a porcine model by using retrospective respiratory gated 4D-computed tomography.
This feasibility study in healthy animals should prove the concept that it is possible to quantitatively assess the effects of different ventilatory settings on the lung parenchyma during ongoing ventilation in respiratory gated 4-dimensional (D)-computed tomography (CT). For this purpose, the influence of different tidal volumes and positive end-expiratory pressure (PEEP) on quantitative assessment of lung volumes (LVs) and lung compartments was analyzed. ⋯ Using a new 4D-CT technique we were able to demonstrate the effect of different ventilation settings on the whole lung during the whole respiratory cycle. The disadvantages of static lung imaging or dynamic 2D-CT can be overcome. The possibility of quantitative evaluation of the whole lung and direct visualization and measurement of recruitment during different ventilation settings might be a great benefit for patients suffering from inhomogeneous lung injury and failure.
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Investigative radiology · May 2008
Comparative StudyQuantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques.
The goal of the present study was the assessment of pancreatic and hepatic fat content applying 2 established magnetic resonance (MR) imaging techniques: in-phase/opposed-phase gradient-echo MR imaging and fat-selective spectral-spatial gradient-echo imaging. Results of both approaches were compared, and influences of T1- and T2*-related corrections were assessed. The possibility of a correlation between pancreatic lipomatosis and liver steatosis was investigated. ⋯ The presented results suggest that both methods are reliable tools for pancreatic and hepatic fat quantification. However, for reliable assessment of quantitative fat by the in-phase/opposed-phase technique, an additional measurement of T2* seems crucial.
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Investigative radiology · May 2008
Noncontrast 3D steady state free precession magnetic resonance angiography of the thoracic central veins using nonselective radiofrequency excitation over a large field of view: initial experience.
To evaluate the feasibility of three-dimensional (3D) steady state free precession (SSFP) magnetic resonance angiography (MRA) using nonselective radiofrequency excitation for the assessment of thoracic central veins. ⋯ Free breathing navigator-gated noncontrast 3D SSFP MRA with nonselective radiofrequency excitation provides high image quality and sufficient SNR and CNR for confident evaluation of thoracic central veins.
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Investigative radiology · May 2008
Comparative Study Clinical TrialPositron emission tomography/computed tomography and whole-body magnetic resonance imaging in staging of advanced nonsmall cell lung cancer--initial results.
To evaluate and compare positron emission tomography/computed tomography (PET/CT) with whole-body magnetic resonance imaging (wbMRI) in the correct staging of patients with advanced nonsmall cell lung cancer (NSCLC). ⋯ In the correct staging of advanced NSCLC, PET/CT has advantages in N-staging. This is of high relevance for therapy planning. WbMRI especially using volume interpolated breathhold examination sequences, has certain advantages in T-staging.