Investigative radiology
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Investigative radiology · May 1990
Detection of thoracolumbar vertebral body destruction with lateral spine radiography. Part I: Investigation in cadavers.
Despite few and inconclusive studies, radiography is generally believed to be insensitive for detection of osteolytic lesions of the spine. A more detailed investigation was undertaken to study the detectability of laboratory-produced osteolytic lesions in cadaveric thoracolumbar vertebral bodies using conventional lateral radiographs. The radiographs were presented to four radiologists in two sessions over a two month period. ⋯ Lesions were grouped into three relative size categories: 18% to 25%, 26% to 40%, and 41% to 60% of transverse vertebral body diameter. The mean increase in ROC area between the small and large lesions was 0.29 (P less than 0.04) for the composite films and 0.16 (P less than 0.05) for the individual films. In the composite study, all readers showed significant (P less than 0.05) increases in lesion detection in spines reflecting large increases (P less than 0.01) in bone mineral content.(ABSTRACT TRUNCATED AT 250 WORDS)
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A new module of instruction for diagnostic imaging with emphasis on cross-sectional anatomy was developed within the existing course of gross anatomy for freshmen medical students. Two lectures introduced radiation protection, radiology history, and the basic principles of computed tomography, magnetic resonance imaging, ultrasound, and radiograph image production. ⋯ Relevant exhibits complemented cadaver dissection. Testing established that significant improvement occurred in the students' ability to identify anatomic structures on diagnostic images.
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Investigative radiology · Nov 1989
Ultrasound detection of differences in density. Explanation of the ureteric jet phenomenon and implications for new ultrasound applications.
Flow of urine from the ureter into the bladder can be encountered during routine sonographic examination of the pelvis. The findings include a stream of hyperechogenic foci spurting into the bladder in real time with the production of a frequency shift during Doppler examination. We have demonstrated that visualization of this phenomenon, at least in part, reflects differences in density and associated compressibility changes between urine in the bladder and in the ureter, and need not be dependent upon flow velocity or other previously hypothesized parameters. The clinical utility of these reproducible and measurable phenomena is explored.
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Investigative radiology · Oct 1988
An experimental evaluation of response to contrast media: Pantopaque, iopamidol, and iohexol in the subarachnoid space.
Myelography in dogs was performed with Pantopaque, iopamidol and iohexol. The effects of these agents were evaluated by histologic study of the brain, spinal cord, and meninges four months after the procedure. ⋯ No apparent protection against Pantopaque arachnoiditis was provided by either intrathecal or intramuscular methylprednisolone. We found no histologic evidence of arachnoiditis in animals examined with iopamidol and iohexol.
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Investigative radiology · Apr 1988
Comparative Study Clinical Trial Controlled Clinical TrialA blinded clinical comparison of MR imaging and CT in neuroradiology.