Parkinsonism & related disorders
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Parkinsonism Relat. Disord. · Jul 2007
ReviewDeep brain stimulation of globus pallidus internus for dystonia.
Neuromodulation is the functional modification of neural structures through the use of electrical stimulation. Its most clinically applicable use is deep brain stimulation (DBS) of basal ganglia structures in Parkinson's disease (PD) and essential tremor (ET). ⋯ In comparison to the effects seen in PD, the improvement in dystonic postures appear to differ in several ways--delay of clinical benefit, higher voltage requirements, and varied stimulator settings. In this review, the authors discuss the clinical characteristics, pathophysiology, microelectrode recording (MER) signatures, optimal surgical targets, programming parameters and outcomes in dystonia.
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Parkinsonism Relat. Disord. · Jul 2007
Electronic motor function diary for patients with Parkinson's disease: a feasibility study.
Parkinson's disease (PD) studies often measure daily motor function with paper diaries resulting in issues of compliance and reliability. The feasibility and compliance of PD patients using electronic diaries were examined. ⋯ Entry compliance was 99.98% within 24h and average response time during awake hours was 63 min. Electronic diaries could be operated by PD patients, provided valuable information about response patterns and resulted in average response compliance of approximately 1h.