Parkinsonism & related disorders
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Parkinsonism Relat. Disord. · Sep 2013
Dissociations among daytime sleepiness, nighttime sleep, and cognitive status in Parkinson's disease.
Daytime and nighttime sleep disturbances and cognitive impairment occur frequently in Parkinson's disease (PD), but little is known about the interdependence of these non-motor complications. Thus, we examined the relationships among excessive daytime sleepiness, nighttime sleep quality and cognitive impairment in PD, including severity and specific cognitive deficits. ⋯ Daytime sleepiness in PD, but not nighttime sleep problems, is associated with cognitive impairment in PD, especially in the setting of dementia, and attention/working memory, executive function, memory, and visuospatial deficits. The presence of nighttime sleep problems is pervasive across the PD cognitive spectrum, from normal cognition to dementia, and is not independently associated with cognitive impairment or deficits in cognitive domains.
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Parkinsonism Relat. Disord. · Sep 2013
Measuring functional impact of cognitive impairment: validation of the Parkinson's disease cognitive functional rating scale.
Little is known on the impact of cognitive impairment on instrumental activities of daily living (IADL) in pre-dementia stages of Parkinson's disease (PD). ⋯ Cognitive impairment exerts measurable impact on IADL in ND-PD patients that can be reliable measured with the PD-CFRS, a PD-validated instrument that can be useful in clinical and research settings.
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Parkinsonism Relat. Disord. · Sep 2013
Letter Case ReportsUnusual movement disorders in spinocerebellar ataxias.