Parkinsonism & related disorders
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Parkinsonism Relat. Disord. · Jun 2020
Parkinson's disease motor subtypes and bilateral GPi deep brain stimulation: One-year outcomes.
We aimed to explore the differences in motor symptoms and quality of life (QOL) outcomes following bilateral globus pallidus internus deep brain stimulation (GPi DBS), across well-defined motor subtypes of Parkinson's disease (PD), to improve clinical decision making. ⋯ Bilateral GPi DBS was effective for advanced PD patients regardless of motor subtypes. Greater tremor improvement in the TD patients accounted for greater Off-medication motor improvement. Longer-term GPi DBS outcomes across different motor subtypes and brain targets should be further studied.