Parkinsonism & related disorders
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Parkinsonism Relat. Disord. · Sep 2013
Letter Case ReportsUnusual movement disorders in spinocerebellar ataxias.
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Parkinsonism Relat. Disord. · Jul 2013
Surgical targets for dystonic tremor: considerations between the globus pallidus and ventral intermediate thalamic nucleus.
Dystonic tremor (DT) is characterized by coexisting tremor and abnormal dystonic posturing in the same segment. DT is often medically refractory and DBS is an important therapeutic option. However, the optimal surgical target for DT remains uncertain with Vim, GPi and zona incerta previously reported as effective. ⋯ The best results for tremor control were observed in patients with Vim DBS but they had persisting mild dystonia. Patients with GPi DBS had average DT improvement by approximately 50% but their dystonia symptoms were markedly improved. We propose that the patients with DT with a mild dystonia should be considered for Vim DBS procedure and the coexistence of severe DT and dystonia may be successfully controlled by combined GPi and Vim DBS surgeries.
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Parkinsonism Relat. Disord. · Jul 2013
Cerebral white matter hyperintensity in Parkinson's disease: a major risk factor for mild cognitive impairment.
Mild cognitive impairment (MCI) and dementia contribute to a poor quality of life among patients with PD. The influence of cerebral ischemia as a risk factor for MCI in PD has not been adequately investigated. To address this issue, we examined the influence of the volume and distribution of white matter hyperintensity (WMH) as a risk factor for MCI in early PD. ⋯ WMH is an important risk factor for PD-MCI independent of vascular risk factors. PD patients with WMH should be regularly screened for MCI.