European journal of medical research
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When initiated in anemic hypoxia, hyperoxic ventilation (ventilation with pure O2, FiO2 1.0, HV) reverses hypoxia-induced ECG-changes and enables survival for several hours. The quantification of the HV-induced gain in anemia tolerance and particularly the Hb-equivalent of HV in this situation are unknown. ⋯ HV initiated in anemic hypoxia creates a margin of safety for myocardial tissue oxygenation and thus further increases anemia tolerance. The Hb equivalent of HV in this situation amounts to approximately 1g/dl.
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Clinical Trial
Cerebral perfusion pressure for prediction of recurrent intracranial hypertension after primary decompressive craniectomy.
Decompressive craniectomy (DC) with dural grafting may be performed in patients with moderate (Glasgow-Coma-Scale [GCS] score 9-12 points) or severe traumatic brain injury (TBI; GCS score
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Comparative Study Clinical Trial
Heavy-weight versus low-weight polypropylene meshes for open sublay mesh repair of incisional hernia.
The introduction of retromuscular, preperitoneal sublay technique using polypropylene (PP) meshes had significantly decreased the recurrence rates after open incisional hernia repair. Nevertheless, recent data of single institutions reported about non-acceptable high hernia recurrences. The objective of this study was to determine early complications and the long-term course of patients who underwent open sublay hernia repair using heavy-weight versus low-weight PP meshes. ⋯ Large pore-sized low-weight PP meshes composed of multifilaments are clearly to be favoured over large pore-sized, monofilament heavy-weight PP meshes because of better abdominal wall compliance and less chronic pain. However, both types of meshes are convincing due to high tensile strength and low recurrence rates in the long-term run.
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Clinical Trial
Long-term improvement in pain coping for cLBP and gonarthrosis patients following body needle acupuncture: a prospective cohort study.
Little is known about potential long-term effects of body acupuncture. The aim of the study was to determine such long-term effects 3 and 6 months after the end of a course of acupuncture treatment for chronic low-back pain (cLBP) or chronic pain caused by gonarthrosis. ⋯ Pain tolerability was significantly improved after acupuncture and remained so up to 6 months after treatment. The mean scores of almost all questionnaires did not change significantly between 3 and 6 months. We therefore conclude that acupuncture had a long-term effect on important aspects of cognitive and emotional pain coping.
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Comparative Study Clinical Trial
Impact of intraoperative myocardial cellular damage on early hemodynamics after off-pump versus on-pump coronary artery bypass surgery.
Due to the surgical trauma a small amount of myocardial cellular damage is inherent during coronary artery bypass grafting (CABG). The purpose of the present study was to assess the degree of myocardial cellular damage after off-pump (OPCAB) and on-pump CABG (ONCAB) as measured by cardiac troponin I (cTnI), creatine kinase (CK), its MB isoenzyme (CK-MB) and myoglobin (Myo) and to examine its impact on early hemodynamics after surgery. ⋯ Off-pump surgery results in equal early hemodynamics despite a significantly lower release of cTnI and CK, suggesting a reduced myocardial cell damage as compared to ONCAB surgery.