Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
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Because vitamin D deficiency has been previously reported in patients with systemic lupus erythematosus (SLE), we decided to examine the prevalence of vitamin D deficiency in Thai SLE patients, to identify possible independent factors affecting serum 25-hydroxyvitamin D(2) and D(3) [25(OH)] vitamin D levels, and to examine the associations of serum 25(OH) vitamin D and disease activity and damage in Thai SLE patients. ⋯ Vitamin D deficiency and insufficiency are common in SLE patients despite more than half of them taking vitamin D supplementations. Higher serum creatinine level and higher current daily glucocorticoid dose are associated with lower serum 25(OH) vitamin D levels. These patients may require higher doses of vitamin D supplementations.
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Case Reports
Total hip arthroplasty in a 17-year-old girl with progressive pseudorheumatoid dysplasia.
Progressive pseudorheumatoid dysplasia is an autosomal recessively inherited skeletal disease. Progressive pseudorheumatoid dysplasia can involve multiple synovial joints, which then develop structural deformity and articular dysfunction. ⋯ Total hip arthroplasty was performed to treat persistent pain and stiffness by reconstructing a functional joint. Although we found arthroplasty to be an effective way of reconstructing a functional joint, treatment of the underlying cause is urgently required for this disease in the future.