Annali italiani di chirurgia
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During extracorporeal cardiac surgery it is difficult to measure the severity of metabolic acidosis thru arterial bloods gas determination. During bypass surgery a decrease in Colloidosmotic Pressure (COP) may influence the degree of acidosis. We studied 90 patients in whom the following parameters were measured before, 30 minutes after beginning bypass, immediatly after bypass, upon arriving bypass, upon arriving in the Intensive Care Unit (ICU) and upon discharge (ICU): pH, lactic, acid, pO2, pCO2, base excess correlating them with COP. ⋯ A greater COP was found with a lower blood lactic acid levels. We recommend the use of colloids perfusion as priming fluid instead of electrolytes solutions, specially in patients in extreme ages and also in those in whom a prolonged bypass time is foreseen. This may prevent an increase in blood lactic acid levels.
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Clinical Trial
[Evaluation of the tolerance of a lipid emulsion administrated during total parenteral nutrition in surgical patients].
Tolerance's evaluation of a lipid emulsion given in course of parenteral total nutrition in surgical patient's. The first fat emulsions for intravenous application were thrown on the market in the 1920's years. ⋯ They also suggest, on the same time, a protocol for the survey of these reactions. The results suggest a good tolerance to Lipofundin S intravenous administration and no influence on haematic biochemical parameters.