Heart : official journal of the British Cardiac Society
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Randomized Controlled Trial Comparative Study
Fatty acid binding protein 4 predicts left ventricular mass and longitudinal function in overweight and obese women.
To explore whether increased adipocyte-derived serum fatty acid binding protein 4 (FABP4) predisposes to cardiac remodelling and left ventricular dysfunction in human obesity. ⋯ In overweight and obese women, FABP4 showed an independent association with parameters of left ventricular remodelling.
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To determine the cost-effectiveness of transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR) in a high-risk aortic stenosis (AS) population. ⋯ TAVI is likely to be a cost-effective treatment for high-risk patients with AS compared with the reference standard of SAVR. However, uncertainty surrounding the long-term outcomes for TAVI patients remains; this could have a substantive impact on estimates of cost-effectiveness.