Heart : official journal of the British Cardiac Society
-
To identify functional aortic regurgitation (FAR) determinants in patients with ascending thoracic aortic aneurysm (ATAA) and surgically confirmed normal aortic valve anatomy. ⋯ The diastolic tenting of aortic leaflets is strongly related to FAR severity in patients with ATAA. The mismatch of STJ/A is significantly associated with diastolic leaflet tenting and its correlated valve regurgitation, independently of the actual ATAA dimension. These findings provide new insight into the mechanism of FAR arising from ATAA.
-
Multicenter Study
Sex-related differences in the presentation, treatment and outcomes among patients with acute coronary syndromes: the Global Registry of Acute Coronary Events.
To assess whether sex differences exist in the angiographic severity, management and outcomes of acute coronary syndromes (ACS). ⋯ Women with ACS were more likely to have cardiovascular disease risk factors and atypical symptoms such as nausea compared with men, but were more likely to have normal/mild angiographic coronary artery disease. Further study regarding sex differences related to disease severity is warranted.
-
Randomized Controlled Trial Multicenter Study
Cost-effectiveness of a disease management programme for secondary prevention of coronary heart disease and heart failure in primary care.
To determine if a disease management programme for patients with coronary heart disease and heart failure represents an efficient use of health services resources. ⋯ The use of a nurse-led disease management programme is associated with increased costs in other coronary heart disease-related services as well as for the costs of the clinics. They are also associated with improvements in health. Even in the short term these disease management programmes may represent a cost-effective service, as additional QALY are generated at an acceptable extra cost.
-
Multicenter Study
The Northern Ireland Public Access Defibrillation (NIPAD) study: effectiveness in urban and rural populations.
To assess the impact of mobile automated external defibrillators (AEDs) on out-of-hospital cardiac arrests (OHCAs) in urban and rural populations. ⋯ Despite improvement in CRI there was no impact on survival (witnessed arrest 32.8%, VF 15.6%).
-
Multicenter Study
Clinical predictors of cardiac syncope at initial evaluation in patients referred urgently to a general hospital: the EGSYS score.
To develop, in patients referred for syncope to an emergency department (ED), a diagnostic score to identify those patients likely to have a cardiac cause. ⋯ A simple score derived from clinical history can be usefully employed for the triage and management of patients with syncope in an ED.