Heart : official journal of the British Cardiac Society
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Multicenter Study
Socioeconomic disparities in prehospital factors and survival after out-of-hospital cardiac arrest.
It remains unknown whether patient socioeconomic factors affect interventions and survival after out-of-hospital cardiac arrest (OHCA), and whether a socioeconomic effect on bystander interventions affects survival. Therefore, this study examined patient socioeconomic disparities in prehospital factors and survival. ⋯ Overall, lower socioeconomic status was associated with poorer prehospital factors and survival after OHCA that was not explained by patient or cardiac arrest-related factors.
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Multicenter Study Comparative Study
Monitoring indirect impact of COVID-19 pandemic on services for cardiovascular diseases in the UK.
To monitor hospital activity for presentation, diagnosis and treatment of cardiovascular diseases during the COVID-19) pandemic to inform on indirect effects. ⋯ Substantial reductions in total and cardiovascular activities are likely to contribute to a major burden of indirect effects of the pandemic, suggesting they should be monitored and mitigated urgently.
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Randomized Controlled Trial Multicenter Study
Limit of detection of troponin discharge strategy versus usual care: randomised controlled trial.
The clinical effectiveness of a 'rule-out' acute coronary syndrome (ACS) strategy for emergency department patients with chest pain, incorporating a single undetectable high-sensitivity cardiac troponin (hs-cTn) taken at presentation, together with a non-ischaemic ECG, remains unknown. ⋯ The LoDED strategy facilitates safe early discharge in >40% of patients with chest pain. Clinical effectiveness is variable when compared with existing rule-out strategies and influenced by wider system factors.
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Multicenter Study Comparative Study
Mid-regional proatrial natriuretic peptide for predicting prognosis in hypertrophic cardiomyopathy.
N-terminal probrain natriuretic peptide (NT-proBNP) predicts mortality and the development of heart failure in hypertrophic cardiomyopathy (HCM). Mid-regional proatrial natriuretic peptide (MR-proANP) is a stable by-product of production of atrial natriuretic peptide. We sought to compare the prognostic value of MR-proANP and NT-proBNP in HCM. ⋯ MR-proANP emerges as a valuable biomarker for the prediction of death and heart failure related events in patients with HCM.
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Multicenter Study Observational Study
Characteristics and outcomes of adults with chronic obstructive pulmonary disease and atrial fibrillation.
Chronic obstructive pulmonary disease (COPD) is associated with the development of atrial fibrillation (AF), and may complicate treatment of AF. We examined the association between COPD and symptoms, quality of life (QoL), treatment and outcomes among patients with AF. ⋯ NCT01165710.