Heart : official journal of the British Cardiac Society
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This NICE technology appraisal guidance considers the clinical and cost effectiveness of the use of alteplase for acute ischaemic stroke.
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Comparative Study
Fetal ECG: a novel predictor of atrioventricular block in anti-Ro positive pregnancies.
Approximately 2.8% of pregnancies are Ro/La antibody positive. 3-15% of fetuses develop complete heart block (CHB). First-degree atrioventricular heart block (1 degrees AVB) is reported in a third of Ro/La fetuses but as most have a normal postnatal ECG this may reflect inadequacies of Doppler measurement techniques. ⋯ zPR is better than mPR at differentiating between normal and prolonged PR intervals, suggesting that fECG is the diagnostic tool of choice to investigate the natural history and therapy of conduction abnormalities in Ro/La pregnancies.
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Editorial Comment
Percutaneous coronary revascularisation: is it ever worth what it costs?
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More than 50% of patients initially resuscitated from out-of-hospital cardiac arrest die in hospital. ⋯ Estimation of serum S-100 concentration after out-of-hospital cardiac arrest can be used to identify patients at risk of significant cognitive impairment at discharge. Serum S-100 and NSE concentrations measured 24-48 hours after cardiac arrest provide useful additional information.