Annals of internal medicine
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Randomized Controlled Trial Multicenter Study Clinical Trial
Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial.
To determine the efficacy of a corticosteroid in reducing the short-term mortality of patients with severe alcoholic hepatitis. ⋯ Methylprednisolone therapy decreases short-term mortality in patients with severe alcoholic hepatitis manifested either by spontaneous hepatic encephalopathy or a markedly elevated discriminant function value.