Annals of internal medicine
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Randomized Controlled Trial Multicenter Study Clinical Trial
Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma. A randomized, controlled trial. Montelukast/Beclomethasone Study Group.
Oral leukotriene receptor antagonists have been shown to have efficacy in chronic asthma. ⋯ Although beclomethasone had a larger mean effect than montelukast, both drugs provided clinical benefit to patients with chronic asthma. This finding is consistent with the use of these agents as controller medications for chronic asthma.
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Comparative Study
A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group.
Serum creatinine concentration is widely used as an index of renal function, but this concentration is affected by factors other than glomerular filtration rate (GFR). ⋯ The equation developed from the MDRD Study provided a more accurate estimate of GFR in our study group than measured creatinine clearance or other commonly used equations.
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Cheyne-Stokes respiration is characterized by periodic breathing that alternates with hypopnea or apnea. ⋯ Theophylline may be a rapid and effective therapy for life-threatening Cheyne-Stokes respiration.