Annals of internal medicine
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Randomized Controlled Trial Multicenter Study Clinical Trial
Mupirocin prophylaxis against nosocomial Staphylococcus aureus infections in nonsurgical patients: a randomized study.
Staphylococcus aureus nasal carriage is a major risk factor for nosocomial S. aureus infection. Studies show that intranasal mupirocin can prevent nosocomial surgical site infections. No data are available on the efficacy of mupirocin in nonsurgical patients. ⋯ Routine culture for S. aureus nasal carriage at admission and subsequent mupirocin application does not provide effective prophylaxis against nosocomial S. aureus infections in nonsurgical patients.
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Randomized Controlled Trial Comparative Study Clinical Trial
Individualizing nicotine replacement therapy for the treatment of tobacco dependence: a randomized trial.
Despite the well-documented efficacy and different pharmacokinetic and pharmacodynamic properties of different forms of nicotine replacement therapy, empirical data are insufficient to guide practitioners in selecting a particular form of treatment for individual patients with tobacco dependence. ⋯ Ethnicity, weight, and level of nicotine dependence may help identify smokers who have greater or lesser abstinence rates with either transdermal or nasal spray nicotine.
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Randomized Controlled Trial Clinical Trial
Health plan members' views about disclosure of medical errors.
Various authorities and national organizations encourage disclosing medical errors, but there is little information on how patients respond to disclosure. ⋯ Patients will probably respond more favorably to physicians who fully disclose medical errors than to physicians who are less forthright, but the specifics of the case and the severity of the clinical outcome also affect patients' responses. In some circumstances, the desire to seek legal advice may not diminish despite full disclosure.
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Comment Letter Comparative Study
Randomized trial of warfarin nomograms.