Annals of internal medicine
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Randomized Controlled Trial Multicenter Study Clinical Trial
Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial.
Central venous catheter-related infections are a significant medical problem. Improved preventive measures are needed. ⋯ The second-generation chlorhexidine-silver sulfadiazine catheter is well tolerated. Antiseptic coating appears to reduce microbial colonization of the catheter compared with an uncoated catheter.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial.
Physicians may use either insulin or exenatide injections for patients with type 2 diabetes mellitus who have poor glycemic control despite taking oral blood glucose-lowering drugs. ⋯ Exenatide and insulin glargine achieved similar improvements in overall glycemic control in patients with type 2 diabetes that was suboptimally controlled with oral combination therapy. Exenatide was associated with weight reduction and had a higher incidence of gastrointestinal adverse effects than insulin glargine.