Annals of internal medicine
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The periodic health evaluation (PHE) has been a fundamental part of medical practice for decades despite a lack of consensus on its value. ⋯ Evidence suggests that the PHE improves delivery of some recommended preventive services and may lessen patient worry. Although additional research is needed to clarify the long-term benefits, harms, and costs of receiving the PHE, evidence of benefits in this study justifies implementation of the PHE in clinical practice.
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Meta Analysis
Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients.
Underutilization of anticoagulant prophylaxis may be due to lack of evidence that prophylaxis prevents clinically important outcomes in hospitalized medical patients at risk for venous thromboembolism. ⋯ Anticoagulant prophylaxis is effective in preventing symptomatic venous thromboembolism during anticoagulant prophylaxis in at-risk hospitalized medical patients. Additional research is needed to determine the risk for venous thromboembolism in these patients after prophylaxis has been stopped.
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Randomized Controlled Trial
Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trial.
It is not known whether rigorous intraoperative glycemic control reduces death and morbidity in cardiac surgery patients. ⋯ Intensive insulin therapy during cardiac surgery does not reduce perioperative death or morbidity. The increased incidence of death and stroke in the intensive treatment group raises concern about routine implementation of this intervention.