Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Intradiscal Glucocorticoid Injection for Patients With Chronic Low Back Pain Associated With Active Discopathy: A Randomized Trial.
Active discopathy is associated with a specific phenotype of chronic low back pain (LBP). Local inflammation has a role in active discopathy-associated symptoms. ⋯ French Ministry of Health.
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Randomized Controlled Trial
Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial.
Interleukin-1 (IL-1), an important proinflammatory cytokine, is suspected to play a role in chronic fatigue syndrome (CFS). ⋯ Interleukin Foundation and an independent donor who wishes to remain anonymous.
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Practice Guideline
Pharmacologic Therapy for Type 2 Diabetes: Synopsis of the 2017 American Diabetes Association Standards of Medical Care in Diabetes.
The American Diabetes Association (ADA) annually updates the Standards of Medical Care in Diabetes to provide clinicians, patients, researchers, payers, and other interested parties with evidence-based recommendations for the diagnosis and management of patients with diabetes. ⋯ This synopsis focuses on recommendations from the 2017 Standards about pharmacologic approaches to glycemic treatment of type 2 diabetes.
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Comparative Study
Survival Comparison of Patients With Cystic Fibrosis in Canada and the United States: A Population-Based Cohort Study.
In 2011, the median age of survival of patients with cystic fibrosis reported in the United States was 36.8 years, compared with 48.5 years in Canada. Direct comparison of survival estimates between national registries is challenging because of inherent differences in methodologies used, data processing techniques, and ascertainment bias. ⋯ U.S. Cystic Fibrosis Foundation.
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Observational Study
Allocation of Internal Medicine Resident Time in a Swiss Hospital: A Time and Motion Study of Day and Evening Shifts.
Little current evidence documents how internal medicine residents spend their time at work, particularly with regard to the proportions of time spent in direct patient care versus using computers. ⋯ Information Technology Department and Department of Internal Medicine of Lausanne University Hospital.