Annals of internal medicine
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The HLA evolutionary divergence (HED), a continuous metric quantifying the peptidic differences between 2 homologous HLA alleles, reflects the breadth of the immunopeptidome presented to T lymphocytes. ⋯ Institut National de la Santé et de la Recherche Médicale.
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The long-term risk for major bleeding in patients receiving extended (beyond the initial 3 to 6 months) anticoagulant therapy for a first unprovoked venous thromboembolism (VTE) is uncertain. ⋯ Canadian Institutes of Health Research. (PROSPERO: CRD42019128597).
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Editorial Comment
Establishing the Efficacy of Midodrine to Prevent Vasovagal Syncope.
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Multicenter Study
Use of Hydroxychloroquine, Remdesivir, and Dexamethasone Among Adults Hospitalized With COVID-19 in the United States : A Retrospective Cohort Study.
Relatively little is known about the use patterns of potential pharmacologic treatments of COVID-19 in the United States. ⋯ National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; and National Institute on Aging.