Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Effect of Sotagliflozin on Total Hospitalizations in Patients With Type 2 Diabetes and Worsening Heart Failure : A Randomized Trial.
In the SOLOIST-WHF (Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure) trial, sotagliflozin, a sodium-glucose cotransporter-1 and sodium-glucose cotransporter-2 inhibitor, reduced total occurrences of cardiovascular deaths, hospitalizations for heart failure, and urgent visits for heart failure relative to placebo by 33%. ⋯ Sanofi at initiation and Lexicon Pharmaceuticals at completion.
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Randomized Controlled Trial
Effects of Tai Chi or Conventional Exercise on Central Obesity in Middle-Aged and Older Adults : A Three-Group Randomized Controlled Trial.
Central obesity is a major manifestation of metabolic syndrome, which is a common health problem in middle-aged and older adults. ⋯ Health and Medical Research Fund.