Annals of internal medicine

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• Ann. Intern. Med. · Dec 2022

  Comment

  In adults, risk for infective endocarditis varied for invasive dental procedures and by antibiotic prophylaxis.

  Thornhill MH, Gibson TB, Yoon F, et al. Antibiotic prophylaxis against infective endocarditis before invasive dental procedures. J Am Coll Cardiol. 2022;80:1029-41. 35987887.

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• Ann. Intern. Med. · Dec 2022

  Editorial

  Endemic Mycoses: Underdiagnosed and Underreported.

  no abstract available

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• Ann. Intern. Med. · Dec 2022

  Randomized Controlled Trial

  Oral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease : A Randomized Controlled Trial.

  Parkinson disease (PD) is associated with α-synuclein (αS) aggregation within enteric neurons. ENT-01 inhibits the formation of αS aggregates and improved constipation in an open-label study in patients with PD. ⋯ Enterin, Inc.

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• Ann. Intern. Med. · Dec 2022

  Randomized Controlled Trial Multicenter Study

  Medical Masks Versus N95 Respirators for Preventing COVID-19 Among Health Care Workers : A Randomized Trial.

  It is uncertain if medical masks offer similar protection against COVID-19 compared with N95 respirators. ⋯ Canadian Institutes of Health Research, World Health Organization, and Juravinski Research Institute.

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• Ann. Intern. Med. · Dec 2022

  Randomized Controlled Trial Multicenter Study

  Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis : A Randomized Controlled Trial.

  End-stage ankle osteoarthritis causes severe pain and disability. There are no randomized trials comparing the 2 main surgical treatments: total ankle replacement (TAR) and ankle fusion (AF). ⋯ National Institute for Health and Care Research Heath Technology Assessment Programme.

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