Annals of internal medicine
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Comment Meta Analysis
SGLT2 inhibitors reduce adverse renal and CV outcomes in patients with or without diabetes.
Nuffield Department of Population Health Renal Studies Group; SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium. Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials. Lancet. 2022;400:1788-801. 36351458.
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Review Meta Analysis
Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes : A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials.
The role of vitamin D in people who are at risk for type 2 diabetes remains unclear. ⋯ None. (PROSPERO: CRD42020163522).
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Comment Meta Analysis
In adults receiving mechanical ventilation, selective decontamination of the digestive tract reduces hospital mortality.
Hammond NE, Myburgh J, Seppelt I, et al. Association between selective decontamination of the digestive tract and in-hospital mortality in intensive care unit patients receiving mechanical ventilation: a systematic review and meta-analysis. JAMA. 2022;328:1922-34. 36286098.
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Clinical Trial
Implantable Defibrillator System Shock Function, Mortality, and Cause of Death After Magnetic Resonance Imaging.
Studies have shown that magnetic resonance imaging (MRI) does not have clinically important effects on the device parameters of non-MRI-conditional implantable cardioverter-defibrillators (ICDs). However, data on non-MRI-conditional ICD detection and treatment of arrhythmias after MRI are limited. ⋯ Johns Hopkins University and National Institutes of Health.