Annals of surgery
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Review Comparative Study
Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair.
This review updates the surgeon about the cellular, matrix, and growth factor components of scarless fetal wound repair. ⋯ Based on the scarless fetal wound repair model, a number of ways in which the matrix and cellular response of the healing adult wound might be manipulated to reduce scarring are reviewed.
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Anatomic variations in the hepatic arteries were studied in donor livers that were used for orthotopic transplantation. ⋯ These data are useful for the planning and conduct of surgical and radiological procedures of the upper abdomen, including laparoscopic operations of the biliary tract.
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Randomized Controlled Trial Clinical Trial
Recombinant human growth hormone accelerates wound healing in children with large cutaneous burns.
Two forms of recombinant growth hormone that accelerate the healing of skin graft donor sites in severely burned children were evaluated. ⋯ Our results indicate that both forms of rhGH are effective in reducing donor site healing time compared with placebo and suggest that accelerating wound healing is of clinical benefit because the patients' own skin becomes rapidly available for harvest and autografting. With this increase in the rate of wound healing, the total length of hospital stay can be reduced by more than 25%.