Annals of surgery
-
Randomized Controlled Trial Multicenter Study Comparative Study
Out-of-hospital hypertonic resuscitation after traumatic hypovolemic shock: a randomized, placebo controlled trial.
To determine whether out-of-hospital administration of hypertonic fluids would improve survival after severe injury with hemorrhagic shock. ⋯ Clinical Trials.gov, NCT00316017.
-
Review Comparative Study
Update on the comparative safety of colloids: a systematic review of clinical studies.
To provide an updated systematic review on the comparative safety of colloids based on recent clinical studies. ⋯ Albumin displayed a more favorable safety profile than HES. Available evidence does not support the existence of consistent safety differences between HES solutions.
-
Randomized Controlled Trial
Skeletal muscle is anabolically unresponsive to an amino acid infusion in pediatric burn patients 6 months postinjury.
To evaluate leg muscle, whole-body muscle, and whole-body nonmuscle protein response to anabolic signaling of amino acids in pediatric burn patients at 6 months after injury. ⋯ In pediatric burn patients at 6 months postinjury, leg muscle protein net deposition is unresponsive to amino acid infusion; and whole-body protein breakdown is significantly higher than in the control group.
-
Comparative Study
Blunt cerebrovascular injury screening with 32-channel multidetector computed tomography: more slices still don't cut it.
We sought to determine the diagnostic accuracy of computed tomographic angiography (CTA) using 32-channel multidetector computed tomography for blunt cerebrovascular injuries (BCVIs). ⋯ Given the devastation of stroke, and high mortality from missed injuries, this study demonstrates that even with more advanced technology (32 vs 16 channel), CTA is inadequate for BCVI screening. Digital subtraction angiography remains the gold standard for the diagnosis of BCVI.
-
Editorial Comment Comparative Study
Computed tomographic angiography for blunt cerebrovascular injuries: don't throw out the baby with the bathwater.