Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jun 2020
Role of TLR4/NF-κB Signalling Pathway in Pulmonary Arterial Hypertension in Patients with Chronic Obstructive Pulmonary Disease.
To determine the role of toll-like receptor 4 (TLR4)/ nuclear factor kappa B (NF-κB) signalling pathway in pulmonary arterial hypertension (PAH) in patients with chronic obstructive pulmonary disease (COPD). ⋯ Inflammatory mechanisms play an important role in the development of PAH in patients with COPD. TLR4/NF-κB signal transduction pathway is involved in the pathogenesis of PAH, and the expression levels of TLR4/NF-κB may reflect the severity of PAH in patients with COPD. Key Words: Toll-like receptor 4, Nuclear factor kappa B, Pulmonary arterial hypertension, Chronic obstructive pulmonary disease, Inflammatory cytokine.
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J Coll Physicians Surg Pak · Jun 2020
Psychological Status of Healthcare Workers during the Covid-19 Pandemic.
To assess the levels of health anxiety and Beck depression according to demographic variables among a sample of healthcare workers during the COVID-19 pandemic. ⋯ During the COVID-19 pandemic, psychological support should be provided to all healthcare workers and working conditions should be corrected to relieve the anxiety and worry. Key Words: COVID-19, Healthcare workers, Health anxiety, Beck depress.
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The aim of this study was to investigate the chest CT findings of coronavirus disease 2019 (COVID-19) from January to February 2020. CT features of six cases, confirmed by reverse transcription polymerase chain reaction (RT-PCR) with COVID-19 disease, were evaluated. Of the six patients, one patient had normal scan. ⋯ While one patient had enlarged mediastinal nodes, no one had pleural effusion. CT can be used as the first choice for early diagnosis of COVID-19 pneumonia. Key Words: Pneumonia, Lung CT scan, COVID-19, Coronavirus infection.
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J Coll Physicians Surg Pak · Jun 2020
Vascular Occlusion Role in the Etiopathohegenesis of Idiopathic Sudden Sensorineural Hearing Loss: Risk Analysis with Hematological Parameters.
To evaluate the concomittant metabolic disorders, mean platelet volume (MPV), and neutrophil to lymphocyte ratio (NLR) in patients with idiopathic sudden sensorineural hearingloss (SSNHL) in comparison to healthy controls. ⋯ High MPV and NLR values are associated with idiopathic SSNHL, suggesting the role of vascular pathologies in etiology of idiopathic SSNHL. Therefore, patients with idiopathic SSNHL should undergo detailed evaluation including hematological indices. Key Words: Idiopathic sudden sensorineural hearing loss, Mean platelet volume, Neutrophil to lymphocytes ratio.
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J Coll Physicians Surg Pak · Jun 2020
Case ReportsMesenteric Lipoma with Volvulus: A Rare Cause of Acute Abdomen in a Child.
Lipoma is benign tumor of mature fat cells and is reported to develop anywhere in the body, e.g. trunk and extremities; however, lipoma in the mesentery of gut is rare, particularly in children. Mesenteric lipomas may be asymptomatic or may present with acute abdomen by leading to volvulus of gut. We report a 6-year female with intestinal obstruction. ⋯ Lipoma was excised and postoperative recovery remained uneventful both in the hospital and on subsequent follow up. We believe mesenteric lipoma should be considered as a cause of volvulus and in differential diagnosis of acute abdomen in children. Key Words: Mesentery, Lipoma, Volvulus, Ileum, Intestinal obstruction.