Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jan 2023
Case ReportsMultiple Brain Abscesses and Mycotic Aneurysm in a Patient with Lupus Nephritis: A Challenging Diagnosis and Treatment Course.
Central nervous system (CNS) septic embolisation is an uncommon but life-threatening condition. Clinicians should be aware of the increased risk of this complication in immunocompromised patients such as those suffering from lupus nephritis (LN). In cases of unexplained fever or neurologic symptoms, septic embolisation should be considered in the differential diagnosis. ⋯ Blood, cerebrospinal fluid, and bronchoalveolar lavage cultures were negative. The patient was treated with a combination of antibiotics and she responded well to treatment. Key Words: Female, Lupus nephritis, Mycotic aneurysm, Brain abscess.
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J Coll Physicians Surg Pak · Jan 2023
Case ReportsAnaesthetic Management of a Child with Propionic Acidemia.
Propionic acidemia (PA) is an inherited autosomal recessive disorder of metabolism caused by a deficiency of propionyl CoA carboxylase, an enzyme that catalyses the conversion of propionyl CoA (PCA) to methylmalonyl CoA, inside the mitochondria, leading to inadequate metabolism of propionyl CoA causing hyperammonemia and metabolic acidosis. Children with PA require dextrose infusion to avoid protein catabolism. This child presented with severe metabolic decompensation and required urgent venous cutdown as there was a failure in establishing a peripheral intravenous line. Key Words: Propionic acidemia, Propionyl CoA, Emergency, Mitochondrial disorder, Organic acidemias.
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J Coll Physicians Surg Pak · Jan 2023
EditorialPrevention is better than Cure - Healthcare Systems in United Kingdom and Pakistan.
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J Coll Physicians Surg Pak · Jan 2023
EditorialLaunch of a New JCPSP Companion Journal Dedicated to Case Reports.
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