Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jan 2025
Observational StudyAlbumin Levels as Prognostic Markers in ICU Mortality.
To evaluate the association of serum albumin levels with short-term mortality in ICU patients, including ICU and 28-day mortality. ⋯ Albumin, Critical care, Mortality.
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J Coll Physicians Surg Pak · Jan 2025
Treatment of Intertrochanteric and Peritrochanteric Fractures: Femoral Head Replacement and Proximal Femoral Locking Plate Implantation.
Null.
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J Coll Physicians Surg Pak · Jan 2025
Gaps and Barriers to the Implementation of Antimicrobial Stewardship Programmes in Hospitals of Pakistan.
Antimicrobial-resistant bacteria are particularly prevalent in Southeast Asia, mainly due to inadequate infection prevention and control (IPC) and the widespread and uncontrolled use of antibiotics. Pakistan is the third largest low-middle-income country (LMIC) user of antibiotics. Antibiotic consumption increased by 65%, from 800 million to 1.3 billion defined daily doses (DDD). ⋯ Additionally, lack of support from hospital administration, limited nationwide health insurance coverage for bacterial cultures, and a lack of surgical centres and microbiology laboratories, information technology (IT) support to collect and analyse AS-related data, reduced availability of pharmacists, ID physicians, and IPC staff for ASP events are the primary contributing factors creating hindrance to the long-term viability of ASP. Briefly, strong hospital leadership support is the major factor for allocating the resources for ASP structures and activities and also for establishing the key performance indicators (KPIs), enforcing compliance with hospital-specific clinical practice guidelines, as well as addressing friction between ASP team members and prescribers. Key Words: Antimicrobial resistance, Antimicrobial stewardship programmes, Infection prevention and control.
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J Coll Physicians Surg Pak · Jan 2025
The Role of 418 Gut Microbiota in Small Cell Lung Cancer Progression: A Mendelian Randomisation Study.
To investigate the causal influence of gut microbiota on small cell lung cancer (SCLC) progression using Mendelian randomisation (MR), providing insights into the gut-lung axis in lung cancer pathology. ⋯ Small cell lung cancer, Gut microbiota, Mendelian randomisation, Causal inference, Cancer epidemiology.
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Null.