Annals of the rheumatic diseases
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Randomized Controlled Trial Comparative Study
Greater reduction of knee than hip pain in osteoarthritis treated with naproxen, as evaluated by WOMAC and SF-36.
To compare the improvement of hip and knee osteoarthritis during treatment with naproxen. ⋯ Patients with knee osteoarthritis improved more with naproxen treatment than patients with hip osteoarthritis, as monitored by WOMAC and the SF-36 domains bodily pain and role-physical. These findings warrant further investigation and strongly suggest that efficacy of treatment of osteoarthritis of knee and hip should be evaluated separately.
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To characterise the immunohistological features of sacroiliitis in ankylosing spondylitis (AS) at different disease stages. ⋯ The immunohistological findings of a limited sample suggest a role for BM in sacroiliitis, for TNFalpha and IL6 in early, active lesions, and for TGFbeta1 at the time of secondary cartilage and bone proliferation.