Annals of the rheumatic diseases
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Randomized Controlled Trial Multicenter Study Comparative Study
Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial.
Long-term immunosuppressive treatment does not efficiently prevent relapses of lupus nephritis (LN). This investigator-initiated randomised trial tested whether mycophenolate mofetil (MMF) was superior to azathioprine (AZA) as maintenance treatment. ⋯ Fewer renal flares were observed in patients receiving MMF but the difference did not reach statistical significance.