Medical science monitor : international medical journal of experimental and clinical research
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Randomized Controlled Trial Comparative Study Clinical Trial
Prone versus supine position in mechanically ventilated children: a pilot study.
It is known that mechanically ventilated patients in the prone position have improved oxygenation compared with those supine. We did a prospective, randomized, controlled trial to evaluate the effect of prone position during mechanical ventilation, on survival in critically ill children. ⋯ Prone position in the first few hours of ventilation significantly improves gas exchange and oxygenation, reduces the mean airway pressures required to ventilate children, and may cause significant improvement in survival. Our study protocol allowed ventilator settings to be changed as needed during ventilation.
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Melanoma represents a significant and growing public health burden worldwide, especially in Caucasian populations. The purpose of this review is to summarize the literature on the relationship between socioeconomic status (SES) and incidence, stage at diagnosis and survival from melanoma. ⋯ Potential explanations for these findings are that high SES individuals may have a higher susceptibility and exposure (e.g., risk behaviors) for developing melanoma, and low SES individuals may have less access to educational campaigns and screening examinations and effective treatment. These differences reflect a disparity in melanoma outcomes across diverse SES populations in many countries.