Medical science monitor : international medical journal of experimental and clinical research
-
Randomized Controlled Trial Comparative Study
Comparison of remifentanil or fentanyl administration during isoflurane anesthesia for coronary artery bypass surgery.
The combination of inhalational agents with moderate doses of fentanyl is popular in cardiac anesthesia. Remifentanil is a new opioid metabolized by non-specific esterases. The aim of our study was to assess whether remifentanil may be superior to fentanyl during isoflurane anesthesia for coronary artery surgery. ⋯ Remifentanil is safe during inhalation anesthesia for coronary artery surgery and it appears to be more effective than fentanyl in blunting hemodynamic response before the initiation of cardiopulmonary bypass surgery.