Tropical medicine & international health : TM & IH
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Trop. Med. Int. Health · Jul 2014
The practice and clinical implications of tablet splitting in international health.
Tablet splitting is frequently performed to facilitate correct dosing, but the practice and implications in low-income settings have rarely been discussed. ⋯ These findings have potential clinical implications on treatment outcome and the development of antimicrobial resistance. Investment by drug companies in a wider range of dosage units, particularly for narrow therapeutic index and critical dosage medicines, is strongly recommended.
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Trop. Med. Int. Health · Jul 2014
Stock-outs of essential health products in Mozambique - longitudinal analyses from 2011 to 2013.
To assess the relationship between health system factors and facility-level EHP stock-outs in Mozambique. ⋯ Facility-level stock-outs of EHPs in Mozambique are common and appear to disproportionately affect those living far from district capitals and near facilities with few health staff. The majority of facility-level EHP stock-outs in Mozambique occur when stock exists at the district distribution centre. Innovative methods are urgently needed to improve EHP supply chains, requesting and ordering of drugs, facility and district communication, and forecasting of future EHP needs in Mozambique. Increased investments in public-sector human resources for health could potentially decrease the occurrence of EHP stock-outs.